We found immunohistochemical or ultrastructural evidence of poxvirus infection in skin-lesion tissue from four patients. All patients reported having direct contact with ill prairie dogs before experiencing a febrile illness with skin eruptions.

The initial Wisconsin cases evaluated in this outbreak occurred in five males and six females ranging in age from 3 to 43 years. Histopathological and electron-microscopical examinations, microbiologic cultures, and molecular assays were performed to identify the etiologic agent. We reviewed medical records, conducted interviews and examinations, and collected blood and tissue samples for analysis from 11 patients and one prairie dog. Zoonotic transmission of a bacterial or viral pathogen was suspected. The most trusted, influential source of new medical knowledge and clinical best practices in the world.ĭuring May and June 2003, an outbreak of febrile illness with vesiculopustular eruptions occurred among persons in the midwestern United States who had had contact with ill pet prairie dogs obtained through a common distributor. Information and tools for librarians about site license offerings. Valuable tools for building a rewarding career in health care. The authorized source of trusted medical research and education for the Chinese-language medical community. The most advanced way to teach, practice, and assess clinical reasoning skills. Information, resources, and support needed to approach rotations - and life as a resident. The most effective and engaging way for clinicians to learn, improve their practice, and prepare for board exams.

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Dog Days by P.J. Reed